National Digestive Diseases
Information Clearinghouse (NDDIC)

A service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health (NIH)

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Digestive Diseases Research and News

October 2012

NIH Collaborates with HBO on Obesity Documentary

HBO Weight of the Nation graphic

The Weight of the Nation documentary series and public awareness campaign features National Institutes of Health (NIH) research showing how obesity affects the country's health and how interventions can turn the tide against obesity and its complications. Launched in April, the series of four documentaries focused on obesity was developed by HBO in consultation with NIH and other major health organizations. The project also includes a three-part HBO Family series for kids, 12 short features, a social media campaign, and a nationwide community-based campaign to mobilize action to move the country to a healthier weight. The films can be viewed for free at leaving site icon.

New NIH Clinical Trial Website Launched for Public, Health Care Providers

The new NIH website, NIH Clinical Research Trials and You, helps people learn more about clinical trials, why they matter, and how to participate. The site also provides educational resources, personal stories, links to clinical trials, and free promotional materials to help raise awareness of clinical trials.

Researchers Study Lean People to Unravel the Complexity of Obesity

Researchers funded by the National Institutes of Health (NIH) are incorporating individuals with ideal body weights into obesity studies leaving site icon. The investigators hope to identify which factors cause some people to become overweight or obese and others to stay lean. Study participants’ food choices, genetic backgrounds, sleeping patterns, and even surrounding temperatures will be examined.

2012 Edition of NIDDK's Annual Scientific Report Now Available

Cover of NIDDK Recent Advances Report

The NIDDK annual scientific report, NIDDK Recent Advances & Emerging Opportunities, is now available. This report highlights examples of NIDDK-supported research advances published in fiscal year 2011.

September 2012

NIH Study to Test Treatment for Fatty Liver Disease in Children

Photo of children smiling

NIH-funded scientists have launched a new clinical trial called Cysteamine Bitartrate Delayed-Release for the Treatment of Nonalcoholic Fatty Liver Disease in Children (CyNCh). The trial will enroll 150 boys and girls ages 8 to 17 with nonalcoholic fatty liver disease, in an effort to find a safe and effective treatment that helps children with fatty liver disease. The participants will receive cysteamine or placebo by mouth twice a day for a year. There are no weight cutoffs or percentiles for the children participating in CyNCh. However, more than 90 percent of the children are expected to be overweight or obese. Children with poorly managed diabetes, heart disease, and other chronic liver diseases will be excluded.

Combination Antiviral Therapy is More Effective for Pediatric Chronic Hepatitis C

A clinical trial has shown that combination therapy with peginterferon and ribavirin is more effective than therapy with peginterferon and placebo in treating chronic hepatitis C in children and adolescents. This trial was conducted at 11 sites throughout the United States. Recent US census results show that 23,048 to 42,296 children are chronically infected with the hepatitis C virus. Eradication of the virus in an infected child has the dual benefits of eliminating social stigma as well as the progression of liver disease.

Functioning Bioengineered Anal Sphincters Implanted in Mice

Photo of lab mice

Building on research that may have implications for future treatment for fecal incontinence, scientists have successfully implanted a physiologically functional bioengineered internal anal sphincter (IAS) in mice. The IAS is a ring-like muscle located just inside the rectum; along with the external anal sphincter, these two muscles keep the anus closed and maintain fecal continence. Loss of IAS muscle tone is a primary cause for the uncontrolled release of stool that occurs in people with fecal incontinence, a condition that places devastating emotional, social, physical, and economic burdens on people who are affected by it.

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Digestive Diseases Research and News is produced by the National Digestive Diseases Information Clearinghouse (NDDIC).

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Page last updated July 23, 2014

The National Digestive Diseases Information Clearinghouse is a service of the National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health.

National Digestive Diseases Information Clearinghouse
2 Information Way
Bethesda, MD 20892–3570
Phone: 1–800–891–5389
TTY: 1–866–569–1162
Fax: 703–738–4929

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